Fibrates medication decreases
triglycerides by reducing liver's production of very low density
lipoprotein (VLDL) and by speed up the removal of triglycerides from
blood.
Available Fibrates medication
- Bezabifrate (Bezalip)
- Fenofibrate (Lofibra, Tricor)
- Gemfibrozil (Lopid)
Who can be benefited by fibrates medication
One study found that patients with heart disease, somewhat elevated triglycerides, and low HDL who took
fibrates had reduced risk for a heart attack.
How to take Fibrates medication
Fibrates are usually given in two daily doses 30 minutes before the morning and evening meals.
Expected benefits of fibrates medication
The
reductions in triglycerides generally are in the range of 20 to 50
percent with increases in HDL cholesterol of 10 to 15 percent.
Possible side effects of fibrates
Fibrates are generally well tolerated by most of the patients. Some rare side effects are
- Stomach upset or diarrhea
- Increased risk of gallstones
- Increases the effect of blood thinning medications
- Anemia
