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A1C test and its memory

Glycated hemoglobin tests carry (memory) of the average blood glucose for the past 2 to 3 months, because the hemoglobin has an approximate 90 day life.

Red blood cell contains hemoglobin its job is to carry oxygen from the lungs to all the cells of the body. Hemoglobin, like all proteins, links up with sugars such as glucose.

If the blood glucose is high, this excess glucose enters in to red blood cells and links up (glycates) with molecules of hemoglobin. If there is more glucose in blood then more hemoglobin got glycated. This measure gives average blood glucose for past 2 to 3 months. We must thank this hemoglobin glycates, because they act as memory and present us an average blood glucose value.

How A1C carries average blood glucose for 2 - 3 months

Hemoglobin containing red blood cell has a life span of approximately 90 day. If one’s blood glucose is maintained high in the first month then more hemoglobin get glycated with excess glucose. Suppose next two month blood glucose level in maintained in normal then there will not be any excess of glucose get glycated with hemoglobin. Still first month glycated hemoglobin’s are still available in the blood.

As said before once the life span of hemoglobin containing red blood cell has completed, it is replaced with the newer one. And thus old glycated hemoglobin data get updated. Thus A1C blood test shows mean value of blood glucose level for last 90 days or 3 months.

Next: A1C benefits and drawbacks


Last modified date 18th September 2009
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