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Biguanide | Metformin 

Biguanide lowers the amount of glucose made by the liver, thus blood glucose levels cannot go too high helps ot treat insulin resistance.

Biguanide

  • Brand name: Glucophage (generic name: metformin),
  • Brand name: Glucophage XR (generic name: metformin—long-acting),
  • Brand name: Riomet (generic name: metformin—liquid).
This type of medicine, which comes in pills or liquid forms.  When insulin works properly, blood glucose levels stay on target and cells get the energy they need. This type of medicine improves cholesterol levels and may help lose weight.

Avoid Metformin / Glucophage, when you

  • have advanced kidney or liver disease,
  • drink excessive amounts of alcoholic beverages,
  • are pregnant, planning to get pregnant, or breastfeeding

Possible side effects of Metformin / Glucophage

  • nausea, 
  • diarrhea, or 
  • upset stomach 
These symptoms happen when you first start taking this type of medicine. These side effects are likely to go away after a while.

Rarely, a serious condition called lactic acidosis occurs as a side effect of taking this medicine. Call your doctor right away if you
  • become weak and tired,
  • become dizzy,
  • feel very cold,
  • have trouble breathing,
  • have unusual muscle pain and stomach problems,
  • have a sudden change in the speed or steadiness of your heartbeat
Sometimes you’ll need to stop taking this type of medicine for a short time so you can avoid developing lactic acidosis. If you have severe vomiting, diarrhea, or a fever, or if you can’t keep fluids down, call your doctor right away. You should also talk with your doctor well ahead of time about stopping this type of medicine if
  • you’ll be having special x rays that require an injection of dye
  • you’ll be having surgery
  • Your doctor will tell you when it’s safe to start taking your medicine again.

Next: D-Phenylalanine | Starlix


Last modified date 1st December 2009
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