Combination Pills

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Diabetes combination medication is in a single pill contain a combination of two classes of diabetes drugs. There are numerous combinations available in the market that best suitable for your specific need, additionally it can lower your overall cost as well as strain to taking the multiple tablets.

Metformin is the common drug in all these pills, because it safely lower glucose production in the liver without any hypoglycemia risk. Additionally, it improves lipid profiles without causing weight gain.

Combination Therapy with Oral Antidiabetic Agents

  • Combination: Metformin and glipizide (Brand name: Metaglip)
  • Combination: Rosiglitazone and glimeperide (Brand name: Avandaryl)
  • Combination: Pioglitazone and metformin (Brand name: ACTOplus Met, ActoPlus Met XR)
  • Combination: Metformin and glyburide (Brand name: Glucovance)
  • Combination: Rosiglitazone and metformin (Brand name: Avandamet)
  • Combination: Pioglitazone and glimepiride (Brand name: duetact)
  • Combination: Sitagliptin and metformin (Brand name: Janumet, Janumet XR)
  • Combination: linagliptin and metformin (Brand name: Jentadueto)
  • Combination: metformin and saxagliptin (Brand name: Kombiglyze XR)
  • Combination: metformin and repaglinide (Brand name: PrandiMet)

What you can expect from combination diabetes medication?

Combinations of two different classes of drug can provide some improved blood-glucose control, and improved patient’s compliance.

  • Metaglip – a combination of metformin and glipizide can decrease FBG by up to by 56.5 mg/dL or 3.139 mmol/l and A1C by up to 2.15 % on average. People taking glipizide or metformin alone did not decrease this much.
  • Avandaryl – a combination of rosiglitazone and glimeperide can decrease FBG by up to by 80 mg/dL or 4.445 mmol/l and A1C by up to 2.5 % on average. People taking rosiglitazone or glimeperide alone did not decrease this much.
  • ACTOplus Met, ActoPlus Met XR – a combination of pioglitazone and metformin can decrease FBG by up to by 42.8 mg/dL or 2.378 mmol/l and A1C by up to 0.64 % on average. People taking Pioglitazone or metformin alone did not decrease this much.
  • Glucovance – a combination of metformin and glyburide can decrease FPG by up to 60 mg/dl or 3.333 mmol/l and hemoglobin A1C by 1.7 to 1.9%. People taking glyburide or metformin alone did not decrease this much.
  • Avandamet – a combination of rosiglitazone and metformin can decrease FBG by up to by 74 mg/dL or 4.111 mmol/l and A1C by up to 2.3 % on average. People taking rosiglitazone or metformin alone did not decrease this much.
  • Duetact – a combination of pioglitazone and glimepiride can decrease FBG by up to by 56.1 mg/dL or 3.117 mmol/l and A1C by up to 1.67 % on average. People taking pioglitazone or glimepiride alone did not decrease this much.
  • Janumet, Janumet XR – a combination of sitagliptin and metformin can decrease FBG by up to by 64 mg/dL or 3.556 mmol/l and A1C by up to 2.3 % on average. People taking sitagliptin or metformin alone did not decrease this much.
  • Jentadueto – a combination of linagliptin and metformin can decrease FBG by up to by 72 mg/dL or 4 mmol/l and A1C by up to 2.0 % on average. People taking linagliptin or metformin alone did not decrease this much.
  • Kombiglyze XR – a combination of metformin and saxagliptin can decrease FBG by up to by 60 mg/dL or 3.333 mmol/l and A1C by up to 2.5 % on average. People taking metformin or saxagliptin alone did not decrease this much.
  • PrandiMet – a combination of metformin and repaglinide can decrease FBG by up to by 56.1 mg/dL or 3.117 mmol/l and A1C by up to 1.67 % on average. People taking metformin or repaglinide alone did not decrease this much.
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