Bitter Melon diabetes | Bitter Melon and Diabetes

Better melon or gourd can naturally increase our body’s ability to utilize glucose, so it is best suitable for type 2 diabetes with insulin resistance.

Bitter gourd or melon (Momordica Charantia)

Bitter gourd is study for diabetes natural treatment shows effective in insulin resistance by increase glucose intake by the body. This diabetes natural herb is believed to regulate the body's ability to process glucose by suppressing the neutral response to the stimuli of sweet tastes.

Bioactive constituents of bitter melon
Momordica charantia has charantin on hydrolysis gives glucose and a sterol, the fruit pulp has Galactouronic. Momordica charantia fruits contains glycosides, saponins, alkaloids, reducing sugars, resins, phenolic constituents, fixed oil and free acids.
Ether extract residue of the alcoholic concentrate from the leaves of better gourd is reported to reveal hypoglycemic activity comparable to that of tolbutamide. The protein termed as P-insulin extracted from Momordica charantia fruits in crystalline form.

Hypoglycemic action mechanisms of Bitter melon

Many experimental findings conclude that Momordica Charantia extract (MCE) exhibited promising anti-diabetic activity. Its anti-hyperlipidemic effect could represent a protective mechanism against the development of atherosclerosis, especially in diabetic condition. Finally, it can be considered that MCE is safe for oral consumption and elicits promising hypoglycemic activity. Hence, it may be pursued for its clinical usefulness in the management of diabetes mellitus and other associated complications.

Scientific evidence of better gourd

Bitter gourd (Momordica Charantia): A dietary approach to hyperglycemia.Authors: Krawinkel MB, Keding GB. Institute: Department of International Nutrition, Institute of Nutritional Science, Justus-Liebig-University, Giessen, Germany. Conclusion: bitter gourd has the potential to become a component of the diet or a dietary supplement for diabetic and prediabetic patients. For further information visit Pubmed (National Center for Biotechnology Information).
Hypoglycaemic activity of saponin fraction extracted from Momordica charantia in PEG/salt aqueous two-phase systems. Authors: Han C, Hui Q, Wang Y. Institute: School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, PR China. Conclusion: The saponin constituents extracted from M. charantia in an aqueous two-phase extraction system induced significant hypoglycaemic activity in hyperglycaemic and normal mice. For further information visit Pubmed (National Center for Biotechnology Information).
Effect of bitter gourd (Momordica charantia) on glycaemic status in streptozotocin induced diabetic rats. Authors: Shetty AK, Kumar GS, Sambaiah K, Salimath PV. Institute: Department of Biochemistry and Nutrition, Central Food Technological Research Institute, Mysore, India. Conclusion: These results clearly provided experimental evidence that dried bitter gourd powder in the diet at 10% level improved diabetic status signifying its beneficial effect during diabetes. For further information visit Pubmed (National Center for Biotechnology Information).
An experimental evaluation of the antidiabetic and antilipidemic properties of a standardized Momordica charantia fruit extract. Authors: Nafisa PC Fernandes, Chakradhar V Lagishetty, Vandana S Panda and Suresh R Naik. Institute: Prin.K.M.Kundnani College of Pharm, Department of Pharmacology and Toxicology, Jote Joy Building, Rambhau Salgaonkar Marg, Cuffe Parade, Mumbai 4000 05, India and Sinhgad Institute of Pharmaceutical Sciences, Sector No. 309/310, Kusgaon(Bk) Lonavala, Pune 410 401, India. Conclusion: Our experimental findings with respect to the mechanism of action of MCE in alloxan diabetic rats suggest that it enhances insulin secretion by the islets of Langerhans, reduces glycogenesis in liver tissue, enhances peripheral glucose utilisation and increases serum protein levels. Furthermore, MCE treatment restores the altered histological architecture of the islets of Langerhans. Hence, the biochemical, pharmacological and histopathological profiles of MCE clearly indicate its potential antidiabetic activity and other beneficial effects in amelioration of diabetes associated complications. Further, an evaluation of its antilipidemic activity in old obese rats demonstrated significant lowering of cholesterol and triglyceride levels while elevating
HDL-cholesterol levels. Also, the extract lowered serum lipids in alloxan diabetic rats, suggesting its usefulness in controlling metabolic alterations associated with diabetes. For further information visit Pubmed central (National Center for Biotechnology Information).

Bitter melon diabetes dosage
The typical dosage of bitter melon is one small, unripe, raw melon or about 50 to 100 ml of fresh juice, divided into 2 or 3 doses over the course of the day. The only problem is that bitter melon tastes extremely bitter. Noted naturopath Michael Murray suggests that you should "simply plug your nose and take a 2-ounce shot."

Bitter melon diabetes safety
As a widely eaten food in Asia, bitter melon is often regarded as safe. Other possible risks include impaired fertility, liver inflammation, and spontaneous abortion.

Bitter gourd diabetes treatment procedure

The bitter gourd is believed to be effective in the treatment of type 2 diabetes with out any major known side effects. Bitter gourd are more effective if taken in combination instead of a single herb. Don’t give up the diabetes conventional medications, take bitter gourd along with it till the glucose level in blood reaches normal. Then slowly reduce the dosage of the conventional medicine and finally discard if possible. For type 1 diabetes the bitter melon can be taken along with insulin therapy, in due coarse insulin shots requirement may be reduced.

Are Bitter melon diabetes safe?

Remember that better melon is herbal medicines, so it too has some side effects. Herbals can also interact with other medicines you are taking. It is best to get registered herbal practitioner's advice before taking herbs, if the treatment is for pregnant women, breast-feeding mother, child or older people.

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