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Diabetes and Ginseng

Ginseng a magical herb trusted over 5000 year for its ability to promote vigor, nourish nervous system, enhances hormonal secretion, lower blood sugar & cholesterol and increases immunity.

Ginseng for diabetes

Ginseng diabetes herb Ginseng root as diabetes herb
Ginseng has a long history of herbal use over 5,000 years. It is one of the most highly regarded herbal medicines gained reputation for being able to promote health, general body vigour and prolong life.  Ginseng can also used to treat diabetes and cholesterol.

Benefits of Ginseng
The ginseng root has many benefits as listed below
  • Vitalize, strengthen, and rejuvenate the entire body.
  • Promote general mental and physical well being.
  • Adaptogen - substances usally plant derived, that assist the body to restore itself to health and work without any unwanted effects even if the recommended dose is widely exceeded.
  • Carminative - An agent that prevents or relieves flatulence (gas in the gastrointestinal tract) and, in infants, may help in the treatment of colic.
  • Expectorant - Promoting or facilitating the secretion or expulsion of phlegm, mucus, or other matter from the respiratory tract.
  • Demulcent - soothe or soften especially to relieve pain in inflamed or irritated mucous membranes.
  • Stimulant and tonic - a drug or similar substance that increases physiological activity (stimulating agent). 
  • It stimulates as well as relaxes the nervous system.
  • Promotes the secretion of hormones.
  • Enhance stamina.
  • Lowers blood sugar and cholesterol.
  • Increases immmunity against diseases. 
  • Used in the treatment of debility by old age or illness, appetite loss, insomnia, stress,  and shock. 
Ginseng is not normally prescribed for pregnant women. The length of treatment for ginseng is around 3 weeks. Excess dosage can cause headaches, restlessness and raised blood-pressure, especially when taken with caffeine, alcohol, turnips and spicy foods.

Different ginsengs available: Asian ginseng(Panax ginseng), Siberian Ginseng(Eleutherococcus senticosus), Japanese Ginseng(Panax japonicus), American Ginseng(Panax quinquefolius)

Bioactive constituent of Ginseng
The dried roots and rhizomes of ginseng contain many important constituents, includes ginseng saponins, ginseng oils and phytosterol, carbohydrates/sugars, nitrogenous substances, amino acids and peptides, organic acids, vitamins and minerals, and certain enzymes. Among these, ginseng saponins is the most active constituents.

Hypoglycemic action mechanism of Ginseng
The hypoglycemic activity of ginseng glycopeptide (GGP) may be attributed to the enhancement of aerobic glycolysis through stimulation of beta-adrenoceptor and increase of various rate-limiting enzyme activities related to tricarboxylic acid cycle.

The mechanisms of American ginseng root in the treatment of diabetes remains a mystery. Initial studies have shown that American ginseng increases insulin production and reduces cell death in pancreatic β-cells.Also, studies have revealed American ginseng's ability to decrease blood glucose in type II diabetes patients.

Scientific clinical evidence of ginseng for diabetes
  1. Ginseng therapy in non-insulin-dependent diabetic patients. By E A Sotaniemi, E Haapakoski and A Rautio at Department of Internal Medicine, University of Oulu, Finland.  Ginseng therapy elevated mood, improved psychophysical performance, and reduced fasting-blood-glucose (FBG) and body weight. The 200-mg dose of ginseng improved glycated hemoglobin, serum PIIINP, and physical activity. Placebo reduced body weight and altered the serum lipid profile but did not alter FBG. Ginseng may be a useful therapeutic adjunct in the management of NIDDM. 
  2. Korean red ginseng stimulates insulin release from isolated rat pancreatic islets. By Kim K, Kim HY at Food Convergence Technology Division, Korea Food Research Institute, Kyonggi-do, Republic of Korea. These findings suggest that Korean red ginseng displays beneficial effects in the treatment of diabetes at least in part via the stimulation of insulin release in a glucose-independent manner. For further information visit Pubmed (National Center for Biotechnology Information). 
  3. Korean red ginseng (Panax ginseng) improves glucose and insulin regulation in well-controlled, type 2 diabetes: results of a randomized, double-blind, placebo-controlled study of efficacy and safety. By Vuksan V, Sung MK, Sievenpiper JL, Stavro PM, Jenkins AL, Di Buono M, Lee KS, Leiter LA, Nam-KY, Arnason JT, Choi M, Naeem A Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, Canada.  Although clinical efficacy, as assessed by HbA1c, was not demonstrated, 12 weeks of supplementation with the selected Korean red ginseng treatment maintained good glycemic control and improved plasma glucose and plasma insulin regulation safely beyond usual therapy in people with well-controlled type 2 diabetes. Further investigation with similarly selected KRG treatments may yield clinical efficacy. For further information visit Pubmed (National Center for Biotechnology Information). 
  4. Effects of American ginseng berry extract on blood-glucose-levels in ob/ob mice. Tang Center for Herbal Medicine Research, Department of Anesthesia and Critical Care, Pritzker School of Medicine, University of Chicago, Illinois 60637, USA. By Xie JT, Aung HH, Wu JA, Attel AS, Yuan CS. Results support in vivo antihyperglycemic and antiobese activity of American ginseng berry extract that may prove to be of clinical importance in the prevention and treatment of Type 2 diabetes. For further information visit Pubmed (National Center for Biotechnology Information). 
  5. Effect of Panax ginseng supplementation on biomarkers of glucose tolerance, antioxidant status and oxidative stress in type 2 diabetic subjects: results of a placebo-controlled human intervention trial. By Ma SW, Benzie IF, Chu TT, Fok BS, Tomlinson B, Critchley LA. Diabetes Obes Metab. Mar 18, 2008. The 'results indicate that there may be some benefit of ginseng supplementation in terms of lowering insulin resistance in type 2 diabetic subjects but not in regard to improving oxidant: antioxidant balance.' They write that the mechanism of action for the positive effects of Asian ginseng supplementation on fasting-blood-sugar-levels and insulin resistance in type 2 diabetic patients seen in this study remains to be determined. Possible mechanisms include effects on 'insulin release from pancreatic beta cells, insulin-stimulated glucose disposal' and increasing insulin sensitivity related to the peroxisome proliferator-activated receptor.
Ginseng diabetes dosage
Generally recommended daily dosage of ginseng is 1 g to 2 g of raw herb, or 200 mg daily of an extract.

Ginseng diabetes safety
Ginseng appears to be nontoxic, both in the short and long-term, according to the results of studies in animals. Reported rare cases of breast tenderness, postmenopausal vaginal bleeding, and menstrual abnormalities associated with ginseng use.
Chinese tradition suggests that ginseng should not be used by pregnant or nursing mothers. Animal study shows that ginseng use by a pregnant mother may cause birth defects.

Ginseng diabetes natural treatment procedure
Ginseng is believed to be effective in the treatment of type 2 diabetes with out any unwanted effects. Don’t give up the diabetes conventional medications, take ginseng along with it till the glucose level in blood reaches normal. Then slowly reduce the dosage of the conventional medicine and finally discard if possible. For type 1 diabetes the ginseng can be taken along with insulin therapy, in due coarse insulin shots requirement may be reduced.

Are Ginseng diabetes safe?
Remember that ginseng is a herbal medicines, so it too has some side effects. Herbals can also interact with other medicines you are taking. It is best to get registered herbal practitioner's advice before taking herbs, if the treatment is for pregnant women, breast-feeding mother, child or older people.

Useful diabetes natural treatments
Diabetes Ginseng Last modified date 8th December 2009
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