Thiazolidinedione

Actos, Avandia (Thiazolidinedione) helps the body to utilize the insulin properly, thus blood glucose level stay on target and body cells get the energy they needed.

Brand name: Actos (generic name: pioglitazone),
Brand name: Avandia (generic name: rosiglitazone).

Thiazolidinediones help your insulin work properly, thus blood glucose levels stay on target and cells get the energy they need.

Avoid Actos / Avandia

If you have heart failure, you should not take this type of pill.

Studies have shown that Avandia is associated with an increased risk for heart attacks and chest pain or discomfort from blocked blood vessels. This type of pill can cause congestive heart failure; Congestive heart failure is a condition in which your heart no longer pumps properly. Then your body keeps too much fluid in your legs, ankles, and lungs.

If you already have congestive heart failure, this pill can make it worse. Call your doctor right away if you have signs of heart failure. Warning signs include;

having swelling in your legs or ankles
gaining a lot of weight in a short time
having trouble breathing
having a cough
being very tired

You should also talk with your doctor about whether to take this type of pill if

you are pregnant, planning to get pregnant, or breast-feeding
you have liver disease

Side effects of Actos / Avandia

Congestive heart failure,
anemia, a condition that can make you feel very tired,
an increased risk of getting pregnant even if you’re taking birth control pills.
Women may have an increased risk of bone fractures.

If you take Actos or Avandia, your health care provider should make sure your liver is working properly. Call your doctor right away if you have any signs of liver disease:

nausea, vomiting,
stomach pain or loss of appetite,
tiredness,
dark-colored urine.

Thiazolidinedione | Actos