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Pyridostigmine is useful in improving muscle strength in patients with a muscle disease (e.g. myasthenia gravis). Therefore, this drug helps to relieve your fatigue, the most common symptom of low bp.


How does pyridostigmine work to raise low blood pressure? Mestinon tablets contain the active ingredient pyridostigmine bromide, which is a type of medicine called an anticholinesterase. It works by prolonging the action of a neurotransmitter called acetylcholine. It functions by preventing the breakdown of an acetylcholine in our body; acetylcholine is necessary for normal muscle function.

Available pyridostigmine brands of low blood pressure medications: Mestinon

Who can use pyridostigmine medications? This medication can be useful to treat postural or orthostatic hypotension; a form of hypotension in which there is a sudden (less than 3 minutes) falls in blood pressure, typically greater than 20/10 mm Hg. It occurs when a person takes a standing position, usually after a prolonged period of rest.

What can expect from pyridostigmine drug medication? It is a treatment for a common form of impaired nerve transmission causing dizziness and fainting when you change position from lying to stand up. Pyridostigmine put no extra stress on your heart when you lie down, thus making it a safe treatment. The goal of low blood pressure treatment is to stop the dizziness, light-headedness and fainting due to autonomic failure (impaired nerve transmission), which causes orthostatic hypotension.

Most of the low blood pressure medications have the tendency to cause high blood pressure when you lie-down. However, pyridostigmine can increase nerve transmission only when you stand up and not while lying-down. Hence, it improves standing blood pressure without increasing lying down pressure.

Pyridostigmine suggested dosage: Oral administration of 60 mg pyridostigmine is effective for the treatment of neurogenic orthostatic hypotension. Both standing blood pressure and peripheral resistance were significantly increased, while the orthostatic fall in blood pressure attenuates. Pyridostigmine is available as a regular tablet, an extended-release (long-acting) tablet, and in syrup form. You can take it once, twice, or several times a day, depending upon the type of tablet.

What are some possible side effects of pyridostigmine drugs? Side effects are of two types; they are muscarinic (nausea, vomiting, diarrhea, abdominal cramps, increased peristalsis, increased salivation, increased bronchial secretions, miosis, and diaphoresis) and nicotinic (muscle cramps, fasciculation and weakness).

Tell your doctor if you are allergy or cold (dexamethasone (Decadron), hydrocortisone (Hydrocortone), magnesium-containing products), heart arrhythmias, taking sleeping pills, intestinal or bladder blockage, asthma, seizures, heart or kidney disease, thyroid problems, or stomach ulcers.

Possible drug interaction with pyridostigmine: Pyridostigmine may interact with aminoglycoside antibiotics (e.g., gentamicin), antiarrhythmic medications (e.g., quinidine), anticholinesterase eye medications (e.g., physostigmine), beta-blockers (e.g., timolol, propranolol), mefloquine, and narcotic pain medications (e.g., morphine, codeine).

If you are panic about medication’s side effects, you can alternatively manage with low blood pressure home remedies. Additionally, you can also consider trying low blood-pressure natural treatments.

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