Renin Inhibitors

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Renin inhibitor medication

Renin inhibitors inhibit the enzyme renin, which results in widening blood vessels, making it easier for the blood to flow, which lowers blood pressure.

Renin inhibitor medication

Commonly prescribed renin inhibitor medications on the market, include:

  • Tekturna (generic name: Aliskiren)

Renin inhibitors have the following actions:

  1. It dilates arteries and veins by blocking angiotensin II formation, thus reduces arterial pressure, preload, and afterload on the heart.
  2. It reduces sympathetic adrenergic activity by blocking angiotensin II on sympathetic nerve release and reuptake of norepinephrine.
  3. It increases renal excretion of sodium and water by blocking angiotensin II in the kidney and by blocking angiotensin II stimulation of aldosterone secretion. Thus lower blood volume, venous pressure, and arterial pressure.

Who should avoid renin inhibitors?

Avoid Renin inhibitors, if you are pregnant or planning for pregnancy or have kidney problems. Also avoid if you are taking water pills (diuretics), other antihypertensive medicines, heart medicines, or medicines to treat a fungus.

What are the side effects of renin inhibitors?

Common side effects of this medicine include dizziness, headache, diarrhea, and stuffy nose.

What are the warning signs of renin inhibitor?

Consult a doctor immediately if you are having: low blood pressure, swelling of face, throat, lips, eyes, or tongue.

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