Peripheral-acting adrenergic antagonists reduce resistance to blood flow in small arteries by inhibiting the release of epinephrine and norepinephrine.
Peripheral Alpha-Adrenergic medications
Peripheral adrenergic inhibitors or antagonists drugs are rarely used unless other medications don't help. Commonly prescribed Peripheral-acting adrenergic blockers medications on the market, include:
- Guanadrel (brand name: Hylorel)
- Guanethidine mono sulfate (brand name: Ismelin)
- Reserpine (brand name: Serpasil)
- Doxazosin (brand name: Cardura)
- Prazosin (brand name: Minipress)
- Terazosin (brand name: Hytrin)
- Tamsulosin (brand name: Flomax)
- Silodosin (brand name: Rapaflo)
- Alfuzosin (brand name: Uroxatral)
- Mecamylamine (brand name: Inversine, Vecamyl)
Who should avoid peripheral alpha-adrenergic blockers?
Elderly and people who have liver problems should discuss with the doctor about the risks of using these medications.
What are the side effects of peripheral alpha-adrenergic blocker?
Potential effects include dizziness, tiredness, lightheadedness, diarrhea, heartburn, vision problems, swelling (of the hands, feet, ankles, or legs), decreased sexual ability and a stuffy nose. Reserpine is commonly used in people with severe hypertension and is often prescribe in combination with a diuretic and a beta-blocker (or another medication that slows the heart rate).
If you have nightmares, insomnia, or depressed, you should stop using the drug.
What are the warning signs of peripheral alpha-adrenergic blocker?
Consult a doctor immediately if having; chest pain, irregular heartbeat, painful erection in men.